COMPARATIVE EFFICACY AND SAFETY OF STATINS FOR OSTEOPOROSIS: A STUDY PROTOCOL FOR A SYSTEMATIC REVIEW AND NETWORK META-ANALYSIS

Comparative efficacy and safety of statins for osteoporosis: a study protocol for a systematic review and network meta-analysis

Introduction Osteoporosis (OP) is a prevalent skeletal disease with high mortality and morbidity, followed by acute and chronic back pain, severe spinal deformity and dysfunction.First-line drugs for OP work through antiresorptive or anabolic mechanisms.Although with good efficacy, these drugs still have certain limitations in clinical application

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Influence of Th1 versus Th2 immune bias on viral, pathological, and immunological dynamics in SARS-CoV-2 variant-infected human ACE2 knock-in miceResearch in context

Summary: Background: Mouse models that recapitulate key features of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection are important tools for understanding complex interactions between host genetics, immune responses, and SARS-CoV-2 pathogenesis.Little is known about how predominantly cellular (Th1 type) versus humoral (Th2 typ

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Defectoscopic Tests of Smoke Mortar Charges

There Heat Management Device are presented selected results of defectoscopic tests on smoke charges confined in the metallic containers inserted in the bodies of 98 mm mortar bombs, using Real Time Rentegenoscopy (RTR) and infrared (IR) thermography.Special attention was taken in terms of structural homogenity and integrity of the smoke charges and

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Structure and Topography Modifications of Treated AISI 316LN Stainless Steel Surfaces after Friction in Dry Sliding Contact by Case Hardening Process

Austenitic stainless is having corrosion resistance property, but certain mechanical applications require improved resistance to wear, inferior cavitation, susceptibility to sensitization.These steels have numerous favourable circumstances for great cryogenic - properties, anti-corrosion, and bio-compatibility.So these steels have a broad applicati

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